This commentator draws a lesson from Luke 13.1-9:
The passage is significant because Jesus constantly avoids letting the question get off-track; he keeps people considering their own sinful state. I am reminded of the standard question that comes up in evangelistic contexts, often to shift the subject: “What about the heathen in Africa [or some other remote area]?” This abstract question is often posed to deflect a personal confrontation with our sin and our need for God. In former days when confronted with such a question, I would wax eloquent on the evangelistic possibilities or lack of possibilities for those distant folk in need. Recently, thinking of this Lukan exchange, I have tended to quickly refocus the question by assuring the listener that God is perfectly capable of handling the needs of those distant folk, but the real question for us to discuss is what we will do with God and his call to turn to him.
There is an answer about the lostness of man and the condemnation that sin brings. Like the author above, however, I tend to emphasize the need of the questioner.
God has made the church responsible for telling everyone about Christ. If they’re lost without hearing the gospel, we bear responsibility for it. Let us therefore fulfill our mission with the news of salvation.
(Oh, in Brazil, the question often is asked about the natives in the depths of the Amazon jungle.)